![]() ![]() More particularly, biomarkers for prediction of the success of the treatments are needed. Although allergen immunotherapy is widely used, there is a need for improvement. Specifically in children, the choice of the method of administration according to the patient's profile is important. Both methods have been extensively studied and have pros and cons. Administration of allergen is currently mostly either by subcutaneous injections or by sublingual administration. ![]() Patients who have had an anaphylactic reaction to hymenoptera venom are also good candidates for allergen immunotherapy. Clinical indications have been well documented for respiratory allergy in the presence of rhinitis and/or allergic asthma, to pollens and dust mites. The clinical efficiency relies on a well-defined immunologic mechanism promoting regulatory T cells and downplaying the immune response induced by allergens. Allergen immunotherapy is a cornerstone in the treatment of allergic children. ![]()
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